Organocatalytic Enantioselective Aminoalkylation of 5‐Aminopyrazole Derivatives with Cyclic Imines

6533b83afe1ef96bd12a7b0c

RESEARCH PRODUCT

Organocatalytic Enantioselective Aminoalkylation of 5‐Aminopyrazole Derivatives with Cyclic Imines

M. Carmen Muñoz Aleix González Del Campo Carlos Vila Gonzalo Blay José R. Pedro Laura Carceller-ferrer

subject

Catàlisi Chemistry Organocatalysis Organic Chemistry Enantioselective synthesis Physical and Theoretical Chemistry Química orgànica Combinatorial chemistry

description

The first enantioselective alkylation of 5‐aminopyrazoles is described with good results. The organocatalytic alkylation of 5‐aminopyrazoles have been accomplished using benzoxathiazine 2,2‐dioxides as electrophiles and a bifunctional squaramide organocatalyst.

year	journal	country	edition	language
2020-11-06	European Journal of Organic Chemistry

https://doi.org/10.1002/ejoc.202001314

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