Thromboembolic complications of COVID-19: the combined effect of a pro-coagulant pattern and an endothelial thrombo-inflammatory syndrome.

6533b850fe1ef96bd12a8642

RESEARCH PRODUCT

Thromboembolic complications of COVID-19: the combined effect of a pro-coagulant pattern and an endothelial thrombo-inflammatory syndrome.

Dario Giambelluca Roberto Cannella M. Arzanauskaite Massimo Midiri Paolo Cabassa Federica Vernuccio F Lombardo Fabio Panzuto

subject

Adult Male medicine.medical_specialty Coronavirus disease 2019 (COVID-19)Pneumonia Viral Disease Thromboembolic complications COVID-19 CT Complications Severe Acute Respiratory Syndrome Communicable Diseases Emerging Article 030218 nuclear medicine & medical imaging Brain Ischemia Thromboplastin 03 medical and health sciences 0302 clinical medicine Intensive care Cause of Death Thromboembolism medicine Humans Radiology Nuclear Medicine and imaging In patient Clinical significance Intensive care medicine Pandemics Aged business.industry pandemic Anticoagulants COVID-19 General Medicine Middle Aged stroke Survival Analysis Italy Radiology Nuclear Medicine and imaging Infectious disease (medical specialty)030220 oncology & carcinogenesis Female Radiography Thoracic business Settore MED/36 - Diagnostica Per Immagini E Radioterapia Coronavirus Infections Pulmonary Embolism Tomography X-Ray Computed Thrombotic complication

description

Coronavirus disease 2019 (COVID-19) is a newly emerging human infectious disease that has quickly become a worldwide threat to health, mainly causing severe acute respiratory syndrome. In addition to the widely described respiratory syndrome, COVID-19 may cause life-treating complications directly or indirectly related to this infection. Among these, thrombotic complications have emerged as an important issue in patients with COVID-19 infection, particularly in patients in intensive care units. Thrombotic complications due to COVID-19 are likely to occur due to a pro-coagulant pattern encountered in some of these patients or to a progressive endothelial thrombo-inflammatory syndrome causing microvascular disease. In the present authors' experience, from five different hospitals in Italy and the UK, imaging has proved its utility in identifying these COVID-19-related thrombotic complications, with translational clinical relevance. The aim of this review is to illustrate thromboembolic complications directly or indirectly related to COVID-19 disease. Specifically, this review will show complications related to thromboembolism due to a pro-coagulant pattern from those likely related to an endothelial thrombo-inflammatory syndrome.

year	journal	country	edition	language
2020-11-01	Clinical radiology

10.1016/j.crad.2020.07.019 https://pubmed.ncbi.nlm.nih.gov/32829885