6533b851fe1ef96bd12a8bb5

RESEARCH PRODUCT

Induction of DNA Repair Genes in Mammalian Cells in Response to Genotoxic Stress

Gerhard FritzBernd KainaMarkus Christmann

subject

chemistry.chemical_compoundchemistryDNA repairGenotoxic StressBase excision repairBiologyDNAGlobal genomic repairCell biologyNucleotide excision repair

description

Genotoxic agents provoke the activation of receptor-triggered pathways and DNA damage-related functions. Here we review data on immediate-early cellular responses and transcriptional activation of DNA repair genes following exposure of mammalian cells to genotoxic stress. Functional consequences of induction of DNA repair genes are also briefly discussed.

yearjournalcountryeditionlanguage
2006-02-10
https://doi.org/10.1007/7050_014