6533b851fe1ef96bd12a8bc8

RESEARCH PRODUCT

Configurations and conformations of torreyol (δ-cadinol), α-cadinol, T-muurolol and T-cadinol

Torbjörn NorinAntti TalvitieAnna-karin Borg-karlson

subject

Cadinolchemistry.chemical_compoundFragmentation (mass spectrometry)ChemistryStereochemistryOrganic ChemistryDrug DiscoveryT-muurololBiochemistryMass spectrometric

description

Abstract The configurations and conformations of torreyol (6; “δ-cadinol”,10α-hydroxy-4-muurolene), α-cadinol (7; 10α-hydroxy-4-cadinene), T-muurolol (8; 10β-hydroxy-4-muurolene), and T-cadinol (9; 10β-hydroxy-4-cadinene) have been determined by an extensive PMR study using lanthanide-induced shifts. Characteristic mass spectrometric fragmentation patterns of muurolols and cadinols are briefly discussed.

https://doi.org/10.1016/s0040-4020(01)92031-9