6533b851fe1ef96bd12a8c33
RESEARCH PRODUCT
Una visión integral del cáncer (III). Evaluación de nuevos biomarcadores y posibilidades de intervención
Luis De La Cruz-merinoFederico LucantoniRosa NogueraRebeca Burgos-panaderoTomás ÁLvaro Naranjosubject
0301 basic medicine03 medical and health sciencesmedicine.medical_specialty030104 developmental biology0302 clinical medicine030220 oncology & carcinogenesismedicineEffective treatmentMedical physicsDiseasePathology and Forensic Medicinedescription
We propose a comprehensive approach to oncological disease, based on a systemic consideration of biology, health and disease. Our two previous review articles focused on tumour microenvironment and the discovery of new biomarkers; here we discuss the practical application of these principles to pathology, through the identification, evaluation and quantitative analysis of new prognostic and predictive factors (Immunoscore, TIME). We also consider the clinical use of promising, better tolerated treatments, such as immunotherapy. The integrative pathologist now has access to the latest improved oncology stratification tools designed to identify effective treatment strategies, based on the natural evolution of clinical and scientific knowledge that transcend the gene-centric theory of cancer.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-04-01 | Revista Española de Patología |