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RESEARCH PRODUCT

A Systematic Nomenclature for the Drosophila Ventral Nerve Cord.

Richard S. MannJames W. TrumanRobert CourtDarren W. WilliamsWyatt KorffJohn C. TuthillMichael H. DickinsonDavid J. MerrittJulie H. SimpsonTroy R. ShirangiJana BörnerMarta CostaGwyneth M CardShigehiro NamikiDavid ShepherdAndrew M. SeedsRod K. MurpheyJ. Douglas ArmstrongCarsten Duch

subject

0301 basic medicineNervous systemanatomytectulumanimal structures1.1 Normal biological development and functioningneuropilSensory systemhemilineageArticle03 medical and health sciences0302 clinical medicineTerminology as TopicmedicineNeuropilPsychologyAnimalsCell LineageInvertebrateontologyNomenclatureNeuronsNeurology & NeurosurgerybiologyGeneral NeurosciencefungiNeurosciencesCommissuremotorneuronbiology.organism_classificationNeuromeretractGanglia Invertebrate030104 developmental biologymedicine.anatomical_structureDrosophila melanogasterVentral nerve cordNeurologicalGangliacommissureinsectCognitive SciencesDrosophila melanogasterNerve NetNeuroscience030217 neurology & neurosurgeryneuromere

description

Drosophila melanogaster is an established model for neuroscience research with relevance in biology and medicine. Until recently, research on the Drosophila brain was hindered by the lack of a complete and uniform nomenclature. Recognizing this, Ito et al. (2014) produced an authoritative nomenclature for the adult insect brain, using Drosophila as the reference. Here, we extend this nomenclature to the adult thoracic and abdominal neuromeres, the ventral nerve cord (VNC), to provide an anatomical description of this major component of the Drosophila nervous system. The VNC is the locus for the reception and integration of sensory information and involved in generating most of the locomotor actions that underlie fly behaviors. The aim is to create a nomenclature, definitions, and spatial boundaries for the Drosophila VNC that are consistent with other insects. The work establishes an anatomical framework that provides a powerful tool for analyzing the functional organization of the VNC.

yearjournalcountryeditionlanguage
2020-09-23Neuron
10.1016/j.neuron.2020.08.005https://pubmed.ncbi.nlm.nih.gov/32931755