6533b851fe1ef96bd12a9688

RESEARCH PRODUCT

Cellular Oxygen Concentration

Rolf Zander

subject

Low oxygenCytochromebiologyChemistryCellular oxygenBiophysicsApparent oxygen utilisationRespiratory chainbiology.proteinLimiting oxygen concentrationPartial pressureIntracellular

description

At low oxygen levels the intracellular or intramitochondrial concentration of molecular oxygen together with the amount of reduced cytochrome oxydase determines the rate of oxygen utilization. Below the so-called “critical oxygen concentration”, i.e. the value, at which a drop in the rate of oxygen uptake has its first evidence, the kinetic is described by the oxygen affinity (Km) of the respiratory chain, i.e. the concentration value for half maximal rate of oxygen uptake.

https://doi.org/10.1007/978-1-4684-3273-2_54