6533b851fe1ef96bd12a9741
RESEARCH PRODUCT
Reaction of 2-acetyltetralone with some esters of benzoic acid
Giacomo FontanaGaetano GiammonaM. GottusoG. AbbateA. Arcoleosubject
inorganic chemicalschemistry.chemical_compoundBicyclic moleculechemistryOrganic ChemistryChlorine atomAlkoxy groupNucleophilic substitutionTriketoneOrganic chemistryAcid hydrolysisSulfuric acidBenzoic aciddescription
In order to investigate the pharmacological screening of a number of pyran-4-ones their synthesis by cyclization with sulphuric acid of the corresponding 1,3,5-triketones has been carried out with high yields. In the course of preparation of the latter the reaction of 2-acetyltetralone with some esters of benzoic acid derivatives has been studied and in particular, for a number of them, an interesting nucleophilic substitution of a chlorine atom with an alkoxy group on a benzenic nucleus has been evidenced.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1986-07-01 | Journal of Heterocyclic Chemistry |