6533b852fe1ef96bd12aa8af

RESEARCH PRODUCT

Clinicopathological analysis of oral mucous autoimmune disease : a 27-year study

Emília Angela Loschiavo ArisawaJanete Dias AlmeidaYasmin Rodarte CarvalhoL.a. Guimaraes Cabral

subject

stomatognathic diseasesErythema multiformeAutoimmune diseasesUNESCO::CIENCIAS MÉDICASMucous membraneLichen planus:CIENCIAS MÉDICAS [UNESCO]PemphigoidPemphigus

description

Made available in DSpace on 2022-04-28T20:39:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-02-01 Objectives: The aim of the present study was to analyze the main clinical and histopathological features of autoimmune diseases with oral manifestations such as oral lichen planus (OLP); mucous membrane pemphigoid (MMP); pemphigus vulgaris (PV) and erythema multiforme (EM). Study design: Retrospective review of 5770 files from the Oral Pathology Laboratory of São José dos Campos Dental School, São Paulo State University (UNESP) comprising a 27-year period from 1974 to 2000. Results: The cases accounted for 64 (1.10%) of 5770 anatomopathological examinations performed over the study period. Among the autoimmune diseases diagnosed, 49 (76.56%) were OLP, 6 (9.37%) were MMP, 5 (7.82%) were EM and 4 (6.25%) were PV. Descriptive statistical analysis was used. Conclusion: The initial manifestations of most autoimmune diseases occur in the oral mucosa. An earlier diagnosis and proper therapeutic protocol will delay the dissemination of the lesions, thus greatly contributing to a better prognosis and quality of life of the patient. © Medicina Oral S. L. Health Science Faculty Vale do Paraíba University - UNIVAP Department of Biosciences and Oral Diagnosis São José Dos Campos Dental School São Paulo State University - UNESP Department of Biosciences and Oral Diagnosis São José Dos Campos Dental School São Paulo State University - UNESP, São José Dos Campos, São Paulo Department of Biosciences and Diagnosis São José Dos Campos Dental School São Paulo State University - UNESP Department of Biosciences and Oral Diagnosis São José Dos Campos Dental School São Paulo State University - UNESP Department of Biosciences and Oral Diagnosis São José Dos Campos Dental School São Paulo State University - UNESP, São José Dos Campos, São Paulo Department of Biosciences and Diagnosis São José Dos Campos Dental School São Paulo State University - UNESP

http://hdl.handle.net/10550/60732