6533b852fe1ef96bd12ab338

RESEARCH PRODUCT

Synthetic Approaches to the Lamellarins—A Comprehensive Review

Dennis ImbriJohannes TauberTill Opatz

subject

lcsh:Biology (General)Coumarinspyrrolesmarine natural productsReviewalkaloidstotal synthesisHeterocyclic Compounds 4 or More Ringslcsh:QH301-705.5lamellarins

description

The present review discusses the known synthetic routes to the lamellarin alkaloids published until 2014. It begins with syntheses of the structurally simpler type-II lamellarins and then focuses on the larger class of the 5,6-saturated and -unsaturated type-I lamellarins. The syntheses are grouped by the strategy employed for the assembly of the central pyrrole ring.

10.3390/md12126142http://www.mdpi.com/1660-3397/12/12/6142