6533b852fe1ef96bd12ab521

RESEARCH PRODUCT

Antioxidant Activity of Vitamin A within Lipid Environments

Luisa TesoriereMaria A. Livrea

subject

VitaminAntioxidantChemistrymedicine.medical_treatmentRadicalRetinoic acidLipid metabolismmedicine.disease_causeLipid peroxidationchemistry.chemical_compoundBiochemistryRetinyl palmitatemedicineOxidative stress

description

New information about deleterious effects of free radicals on cell compartments, and a growing amount of associations between free radicals and various pathological conditions, have produced considerable interest in the biological defense systems against oxidative injury. The antioxidant properties of vitamin A, known for decades (Monaghan and Schmitt, 1932), have been reinvestigated in recent years in chemical as well as in biological systems. Its lipid nature and the localization within the lipophilic compartment of membranes and lipoproteins make vitamin A effective in reducing lipid peroxidation by acting as a chain-breaking antioxidant.

yearjournalcountryeditionlanguage
1998-01-01
https://doi.org/10.1007/978-1-4899-1789-8_5