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RESEARCH PRODUCT

O2 Supply Conditions in Tumor Tissue in Vivo

Peter VaupelGerhard Thews

subject

Pathologymedicine.medical_specialtyIn vivoChemistryTumor WeightmedicineRat kidneyVenous bloodTumor tissue

description

During the last few years O2 supply of tumor tissue has very carefully been investigated using GULLINO’ s model of a “tissue isolated” implantation tumor (GULLINO and GRANTHAM, 1961; GUNTHER et al., 1972; VAUPEL et al., 1971; VAUPEL, 1974). We analysed the O2 supply for a DS-Carcinosarcoma in the rat kidney by two methods: 1. direct measurement of O2 pressures in the tissue by means of gold micro-electrodes, 2. PO2 calculation according to diffusion laws considerring the experimentally determined parameters in the arterial and venous blood.

yearjournalcountryeditionlanguage
1976-01-01
https://doi.org/10.1007/978-1-4684-3273-2_63