6533b853fe1ef96bd12abfa1
RESEARCH PRODUCT
Studies of Preparation and Stability of Liposomes Formed by 1,1'-[(3,5-didodeciloxycarbonyl-4-phenyl-1,4-dihydropyridine-2,6-diil)-dimethylen]Bispyridinium Dibromide
Martins RucinsOksana PetricenkoArkadij SobolevBrigita CekavicusKarlis PajusteAiva PlotnieceMarina GostevaMāra PlotnieceKlavs Pajustesubject
LiposomeChemistryAtomic force microscopySonicationGeneral EngineeringDihydropyridineProbe typeSolventDynamic light scatteringAmphiphilemedicineOrganic chemistrymedicine.drugNuclear chemistrydescription
In this work we describe the studies of preparation and stability of liposomes formed by 1,1'-[(3,5-didodeciloxycarbonyl-4-phenyl-1,4-dihydropyridine-2,6-diil) dimethylebispyridinium dibromide, novel lipid-like compound. The influence of the amount of amphiphilic compound, solvent and sonication time was studied. Liposomes were prepared by dispersing of compound in the corresponding media at a selected concentration by sonication using a probe type sonicator and characterised by atomic force microscopy (AFM) and dynamic light scattering (DLS) methods.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-09-01 | Advanced Materials Research |