6533b853fe1ef96bd12ad451
RESEARCH PRODUCT
Synthesis of Piperidines and Dehydropiperidines
Till OpatzMarco M. Nebesubject
Annulationchemistry.chemical_compound010405 organic chemistryChemistryStereochemistryPiperidine010402 general chemistryRing (chemistry)01 natural sciencesCombinatorial chemistryTopology (chemistry)0104 chemical sciencesdescription
Abstract The present review focuses on strategies for the construction of piperidines and dehydropiperidines, which have appeared in the literature since 2003/2004 through mid-2016. Synthetic methods involving the construction of the six-membered ring from essentially acyclic starting materials in intra- or intermolecular will be highlighted and discussed. In contrast, methods using only the decoration or modification of previously generated pyridines or piperidines will not be part of this review. The published syntheses will be categorized based on the topology of the bond forming events generating the piperidine core.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-01-01 |