6533b853fe1ef96bd12ad8ce
RESEARCH PRODUCT
New Microbe Killers : Self-Assembled Silver(I) Coordination Polymers Driven by a Cagelike Aminophosphine
W. Sabina JarosMatti HaukkaMagdalena FlorekFátima C. M. Guedes Da SilvaJ. L. Armando PombeiroM. Alexander KirillovPiotr Smoleńskisubject
antimikrobiset yhdisteetcoordination polymersmetal-organic frameworks (MOFs)coordination chemistryhopeasilver135-triaza-7-phospaadamantanekompleksiyhdisteetorganometalliyhdisteetpolymeeritantimicrobial materialsdescription
New Ag(I) coordination polymers, formulated as [Ag(μ-PTAH)(NO3)2]n (1) and [Ag(μ-PTA)(NO2)]n (2), were self-assembled as light- and air-stable microcrystalline solids and fully characterized by NMR and IR spectroscopy, electrospray ionization mass spectrometry (ESI-MS(±), elemental analysis, powder (PXRD) and single-crystal X-ray diffraction. Their crystal structures reveal resembling 1D metal-ligand chains that are driven by the 1,3,5-triaza-7-phospaadamantane (PTA) linkers and supported by terminal nitrate or nitrite ligands; these chains were classified within a 2C1 topological type. Additionally, the structure of 1 features a 1D!2D network extension through intermolecular hydrogen bonds, forming a two-dimensional hydrogen-bonded network with fes topology. Furthermore, both products 1 and 2 exhibit remarkable antimicrobial activity against different human pathogen bacteria (S. aureus, E. coli, and P. aeruginosa) and yeast (C. albicans), which is significantly superior to the activity of silver(I) nitrate as a reference topical antimicrobial. peerReviewed
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-01-01 |