6533b854fe1ef96bd12ae1c0
RESEARCH PRODUCT
Studies on the structure of coumarin-modified dextran nanoparticles by fluorescence spectroscopy.
Anne KotiahoPedro FardimThomas HeinzeThomas HeinzeHolger WondraczekMarja Niemisubject
Polymers and PlasticsCycloaddition Reactionta221Organic ChemistryNanoparticleDextransPhotochemistryCoumarinFluorescenceFluorescence spectroscopySolventchemistry.chemical_compoundDextranUltraviolet visible spectroscopySpectrometry FluorescencechemistryCoumarinsMaterials ChemistryNanoparticlesheterocyclic compoundsAbsorption (chemistry)ta116description
The photophysical and photochemical characteristics of nano-scaled particles obtained via solvent displacement from coumarin-modified dextrans were studied by means of absorption- and fluorescence-spectroscopy. The environment-dependent fluorescence emission of the pendant 4-methyl-7-alkoxy coumarin groups was exploited as a probe to gain information about the inner structure of the polysaccharide based nanoparticles. Time-resolved fluorescence measurements showed that the particles had two domains of different polarity and it could be confirmed that the core of the nano-assemblies contained water. Moreover, preliminary experiments were carried out demonstrating the possibility to control the morphology of the nanoparticles by the light induced 2π+2π cycloaddition of the coumarin substituents.
year | journal | country | edition | language |
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2012-12-08 | Carbohydrate polymers |