6533b854fe1ef96bd12aea4e

RESEARCH PRODUCT

Conventional MRI-Derived Biomarkers of Adult-Type Diffuse Glioma Molecular Subtypes: A Comprehensive Review.

Paola FeracoRossana FranciosiLorena PicoriFederica ScalorbiCesare Gagliardo

subject

magnetic resonance imaging (MRI)isocitrate dehydrogenase (IDH)Medicine (miscellaneous)Settore MED/37 - NeuroradiologiaGeneral Biochemistry Genetics and Molecular Biologyadult diffuse glioma

description

The introduction of molecular criteria into the classification of diffuse gliomas has added interesting practical implications to glioma management. This has created a new clinical need for correlating imaging characteristics with glioma genotypes, also known as radiogenomics or imaging genomics. Although many studies have primarily focused on the use of advanced magnetic resonance imaging (MRI) techniques for radiogenomics purposes, conventional MRI sequences remain the reference point in the study and characterization of brain tumors. A summary of the conventional imaging features of glioma molecular subtypes should be useful as a tool for daily diagnostic brain tumor management. Hence, this article aims to summarize the conventional MRI features of glioma molecular subtypes in light of the recent literature.

yearjournalcountryeditionlanguage
2022-10-01Biomedicines
10.3390/biomedicines10102490https://pubmed.ncbi.nlm.nih.gov/36289752