Porous titanium for biomedical applications : an experimental study on rabbits

6533b854fe1ef96bd12aead5

RESEARCH PRODUCT

Porous titanium for biomedical applications : an experimental study on rabbits

Yasmin Rodarte Carvalho Fernanda Oliveira Nascimento Daniel De Oliveira Leite Carlos Alberto Alves Cairo Luana Marotta Reis De Vasconcellos Mario Lima De Alencastro Graça Luis Gustavo Oliveira De Vasconcellos

subject

Morphology (linguistics)Materials science chemistry.chemical_element mechanical properties biomedical Osseointegration Osseointegration Powder metallurgy Materials Testing Animals titanium Porosity General Dentistry Porous titanium Titanium technology industry and agriculture osseointegration Compression (physics)equipment and supplies :CIENCIAS MÉDICAS [UNESCO]Biomechanical Phenomena Compressive strength Otorhinolaryngology chemistry UNESCO::CIENCIAS MÉDICAS Surgery Rabbits Porosity Biomedical engineering Titanium

description

Made available in DSpace on 2013-08-12T18:44:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-03-01 Made available in DSpace on 2013-09-30T18:34:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-03-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T14:04:32Z No. of bitstreams: 0 Made available in DSpace on 2014-05-20T14:04:32Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-03-01 Objective: The aim of this study was to carry out an in vivo assessment of bone ingrowth in two different types of porous titanium -the first being completely porous, and the second with a porous surface and dense nucleus, manufactured by powder metallurgy- and to evaluate their mechanical properties. Study design: Ten scaffolds from each group were submitted to metallographic analysis and compression tests. Next, two scaffolds of each type were inserted into 14 rabbits, which were sacrificed 8 weeks after surgery. The samples were submitted for histological examination. Results: Metallographic analysis revealed interconnected pores, and the average interconnected pore diameter was about 360 mm, with 36% total porosity. The totally porous titanium samples and the titanium samples with porous surface and dense nucleus showed an average compressive strength of 16.19 MPa and 69.27 MPa, respectively. After 8 weeks, the animals showed bone ingrowth, even into the most internal pores. Conclusions: The pore morphology was effective in permitting bone ingrowth in both groups. Titanium scaffolds with a porous surface and dense nucleus showed the best mechanical properties and most adequate interface. State Univ São Paulo, UNESP, Sao Jose dos Campos Sch Dent, Dept Biosci & Buccal Diag, Sao Jose Dos Campos, Brazil CTA, Air & Space Inst, Dept Mat, Sao Jose Dos Campos, Brazil State Univ São Paulo, UNESP, Sao Jose dos Campos Sch Dent, Dept Prostodont & Dent Mat, Sao Jose Dos Campos, Brazil State Univ São Paulo, UNESP, Sao Jose dos Campos Sch Dent, Dept Biosci & Buccal Diag, Sao Jose Dos Campos, Brazil State Univ São Paulo, UNESP, Sao Jose dos Campos Sch Dent, Dept Prostodont & Dent Mat, Sao Jose Dos Campos, Brazil

year	journal	country	edition	language
2010-01-01

http://hdl.handle.net/10550/60383