6533b854fe1ef96bd12aead8

RESEARCH PRODUCT

Molecular topology - dissimilar similarities.

Jorge GalvezRamón García-domenechMaria Galvez-llompartRiccardo Zanni

subject

Molecular StructureDrug DesignDrug DiscoveryMolecular MedicineNanotechnologyComputational biologyMolecular topologyBiologyPharmacological Phenomena

description

The present paper depicts the role of molecular topology in the study of similarity–dissimilarity between molecular structures. It proves that molecular topology represents a very useful tool for getting common patterns of pharmacological activity and hence an efficient approach for the search of novel lead drugs.

10.1016/j.ddtec.2013.05.001https://pubmed.ncbi.nlm.nih.gov/24451637