6533b854fe1ef96bd12aeb8f
RESEARCH PRODUCT
Tissue characterization of benign brain tumors: Use of NMR-tissue parameters
Georg FriesManfred ThelenPeter PfannenstielManfred SchwarzM. JustJürgen BohlHans P. Higersubject
AdenomaPathologymedicine.medical_specialtyBrain NeoplasmsChemistryBiomedical EngineeringBiophysicsBenign brain tumorsBrainNeuroma AcousticTissue characterizationImage EnhancementMagnetic Resonance ImagingModels StructuralCraniopharyngiomaBody WaterHistological diagnosismedicineHumansPituitary NeoplasmsRadiology Nuclear Medicine and imagingMeningiomaProton densityQuantitative analysis (chemistry)description
Abstract To evaluate the potentials of NMR tissue parameters for tissue characterization we investigated 68 patients with benign brain tumors. Tissue parameters were accurately measured by a recently developed interlaced triple sequence. Each individual tumor was characterized by a set of three numbers (relaxation times T 1 and T 2 and proton density Rho). Different tumors exhibited significant overlaps of the three tissue parameters. Therefore a reliable prediction of the histological diagnosis based on the quantitative analysis of tissue parameters alone was not possible. T 2 -prolongation correlated well with water content and “regressive changes” in meningiomas and neuromas.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1988-07-01 | Magnetic Resonance Imaging |