6533b854fe1ef96bd12af23e

RESEARCH PRODUCT

Modulation of MHC Class II Determinants on Rat Langerhans Cells During Short Term Culture

Ursula NeißDetlef BeckerJürgen KnopKonrad Reske

subject

MHC class IIImmune systemintegumentary systemAntigenImmunologybiology.proteinPotencyHigh activationBiologyInvariant chain

description

Epidermal Langerhans cells (LC) are regarded as the most peripheral outpost of the immune system. They play a pivotal role during the onset of an immune response in the skin. One of the principal functions of LC is reflected in their extraordinary potency to present antigen to high activation requiring naive T cells.

https://doi.org/10.1007/978-1-4615-2930-9_5