6533b854fe1ef96bd12afa4e
RESEARCH PRODUCT
[Validity of the use of penbutolol in essential arterial hypertension].
S. PepeG. ScaliciA. D AngeloB. CurialeCorrao SalvatoreC. Agnellosubject
AdultMaleSettore MED/09 - Medicina InternaAdult Aged Blood Pressure/drug effects Diastole Drug Evaluation Female Humans Hypertension/drug therapy* Male Middle Aged Penbutolol/therapeutic use* Propanolamines/therapeutic use* Systole SubstancesSystoleBlood PressureMiddle AgedSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheSettore MED/11 - Malattie Dell'Apparato CardiovascolarePropanolaminesDiastoleHypertensionDrug EvaluationHumansFemalePenbutololAgeddescription
Thirty patients suffering from WHO I-II class slight-moderate essential arterial hypertension were treated with a beta-blocker (Penbutolol) alone and once a day to assess its antihypertensive effectiveness and its affect on heart frequency, lipid metabolism and kidney function. The drug proved highly effective in reducing P.A.S. and P.A.D. values and no negative influence was documented on lipid metabolism, kidney function or heart frequency.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1990-06-01 | Minerva medica |