Optiskā starojuma izplatības modelēšana veselā un patoloģiskā ādā

6533b855fe1ef96bd12b0c65

RESEARCH PRODUCT

Optiskā starojuma izplatības modelēšana veselā un patoloģiskā ādā

subject

hromoforu kartēšana datormodelēšana multispektrālā attēlošana Fizika montekarlo simulācijas

description

Šajā darbā tika izmantotas montekarlo un hromoforu kartēšanas metodes, lai novērtētu iespēju ar to palīdzību izšķirt pigmentētas labdabīgas no onkoloģiskām cilvēka ādas patoloģijām. Pētījumā kopumā tika izmantots gaismas optiskā spektra diapazons robežās no 450 nm līdz 950 nm. Tika veikta literatūras izpēte saistībā ar ādas patoloģiju struktūru un īpatnībām, hromoforu kartēšanas metodi un montekarlo simulāciju metodi. Tika izveidota programmatūra montekarlo simulāciju veikšanai un hromoforu kartēšanai. Balstoties uz literatūras datiem, tika izveidots ādas modelis montekarlo simulāciju veikšanai, un veiktas optisko parametru manipulācijas programmas ievadē, lai gūtu informāciju par katra parametra ietekmi uz rezultējošo absorbcijas spektru. Veikta 50 dažādu ādas patoloģiju multispektrālo attēlu analīze ar izveidoto hromoforu kartēšanas algoritmu. Piedāvāts izšķirt pigmentētas labdabīgas no onkoloģiskām ādas patoloģijām ar inversās montekarlo metodes palīdzību, kā arī izmantojot divu dažādu izšķiršanas indeksu vērtību sadalījumu pēc hromoforu karšu analīzes. Darba rezultāti parāda, ka šīs abas metodes ir noderīgas ādas pigmentēto pataloģiju izšķiršanai.

year	journal	country	edition	language
2017-01-01

https://dspace.lu.lv/dspace/handle/7/36455

PEPhysical Sciences and Engineering
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