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RESEARCH PRODUCT
Asymmetric Hydrogenation of Nonfunctionalized Olefins in Propylene Carbonate—Kinetic or Thermodynamic Control?
Benjamin SchäffnerArmin BörnerSergey P. VerevkinJérôme BayardonWolfgang BaumannVladimir N. Emel’yanenkosubject
ChemistryGeneral Chemical EngineeringKineticsInorganic chemistryAsymmetric hydrogenationGeneral ChemistryKinetic energyIndustrial and Manufacturing EngineeringCatalysisSolventchemistry.chemical_compoundPropylene carbonateOrganic chemistryDichloromethanedescription
Iridium-catalyzed hydrogenations of nonfunctionalized olefins in propylene carbonate as the solvent allow efficient catalysis with much higher enantioselectivities in comparison with dichloromethane which is usually employed for these reactions. Experimental and computational studies of the hydrogenation of 1-methylene-1,2,3,4-tetrahydronaphthalene have been performed to understand the limitation for this reaction.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-12-16 | Industrial & Engineering Chemistry Research |