Synthesis and Anti-Staphylococcal Activity of New Halogenated Pyrroles Related to Pyrrolomycins F

6533b855fe1ef96bd12b12ab

RESEARCH PRODUCT

Synthesis and Anti-Staphylococcal Activity of New Halogenated Pyrroles Related to Pyrrolomycins F

Maria Valeria Raimondi Salvatore Petruso Domenico Schillaci

subject

inorganic chemicals ANALOGS Strain (chemistry)Chemistry Stereochemistry Organic Chemistry STAPHYLOCOCCUS Antibacterial activity Chemical synthesis

description

The chemical synthesis of new halogenated pyrroles related to pyrrolomycins F is described and the anti-staphylococcal activity compared. The replacement of 4′-bromo atom of parent compounds with two chloro atoms at 3′ and 5′ position increase the antibacterial activity against a reference strain of S. aureus.

year	journal	country	edition	language
2007-11-01

10.1002/jhet.5570440626 http://hdl.handle.net/10447/18588

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