6533b855fe1ef96bd12b13ab

RESEARCH PRODUCT

Evolutionary aspects of peroxisomes as cell organelles, and of genes encoding peroxisomal proteins

Norbert LatruffeJoseph Vamecq

subject

OrganellesNuclear ProteinsReceptors Cytoplasmic and NuclearCell BiologyGeneral MedicinePlantsMitochondrionPeroxisomeBiologyMicrobodiesCell biologyEvolution MolecularGene Expression RegulationBiochemistryPhylogeneticsOrganellePeroxisomesAnimalsHumansMicrobodyReceptorTranscription factorGeneTranscription Factors

description

Peroxisomes are present in most eukaryotic cell types, and have different enzymatic content and metabolic functions throughout the life scale. The endosymbiotic origin of these DNA-devoid organelles is supported by evolutionary data concerning genes encoding not only most peroxisomal proteins, but also several transcriptional factors regulating their expression such as peroxisome proliferator-activated receptors.

https://doi.org/10.1016/s0248-4900(00)01083-2