A Photoinduced Cobalt-Catalyzed Synthesis of Pyrroles through in Situ-Generated Acylazirines

6533b855fe1ef96bd12b13cc

RESEARCH PRODUCT

A Photoinduced Cobalt-Catalyzed Synthesis of Pyrroles through in Situ-Generated Acylazirines

Stefan Pusch Danuta Kowalczyk Till Opatz

subject

In situ chemistry 010405 organic chemistry Organic Chemistry Polymer chemistry chemistry.chemical_element 010402 general chemistry Ring (chemistry)01 natural sciences Cobalt 0104 chemical sciences Catalysis

description

Tetrasubstituted pyrroles can be synthesized in a one-pot procedure from isoxazoles. The process includes the photoinduced in situ formation of acylazirines combined with a subsequent cobalt(II)-catalyzed ring expansion with 1,3-diketones.

year	journal	country	edition	language
2016-04-16	The Journal of Organic Chemistry

https://doi.org/10.1021/acs.joc.6b00511

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