Ādas hromoforu kartēšana, izmantojot divu momentuzņēmumu metodi

6533b856fe1ef96bd12b210b

RESEARCH PRODUCT

Ādas hromoforu kartēšana, izmantojot divu momentuzņēmumu metodi

subject

oksi-hemoglobīns deoksi-hemoglobīns melanīns Bēra-Lamberta likums Fizika hromoforu koncentrāciju sadalījums

description

Darba mērķis ir izstrādāt metodi, ar kuru īsā laika posmā var iegūt informāciju par hromoforu koncentrāciju sadalījumu ādā. Darbā tiek apskatītas vairākas ādas patoloģijas. Katra veidojuma analīzei tiek uzņemti divi attēli. Pirmais attēls tiek iegūts, ādu apgaismojot ar trīs dažādu viļņu garumu lāzeriem: 450nm, 525nm un 850nm. Savukārt otrs attēls tiek iegūts, ādu apgaismojot ar diviem dažādu viļņa garuma lāzeriem: 405nm un 656nm. Tālāk attēli tiek sadalīti R, G un B kanālos. Papildus tiek iegūti pieci references attēli, apgaismojot baltu lapu ar katru no lāzeriem. Sadalot arī šos attēlus R, G un B kanālos, rezultātā tiek iegūti 21 monohromatisks attēls, no kuriem tiek aprēķināti spektrālās vājināšanas koeficienti katram izmantotajam viļņa garumam. BēraLamberta vienādojumā, ievietojot zināmos lielumus un attiecīgos ekstincijas koeficientus, tiek aprēķinātas hromoforu kartes. Rezultātā īsā laika posmā tiek iegūtas oksi-hemoglobīna, deoksi-hemoglobīna, melanīna, bilirubīna un lipīdu kartes. Šīs kartes parāda skābekļa koncentrāciju asinīs, melanīna daudzumu un bilirubīna koncentrāciju. Šāda veida neinvazīvo metožu ieviešana dermatoloģijā atvieglo un paātrina ādas sastāva analīzi.

year	journal	country	edition	language
2018-01-01

https://dspace.lu.lv/dspace/handle/7/40544

PEPhysical Sciences and Engineering
- PE2Fundamental Constituents of Matter
  - PE2_1Theory of fundamental interactions
  - PE2_2 Phenomenology of fundamental interactions
  - PE2_3Experimental particle physics with accelerators
  - PE2_4Experimental particle physics without accelerators
  - PE2_6Nuclear, hadron and heavy ion physics
  - PE2_8Gas and plasma physics
  - PE2_5Classical and quantum physics of gravitational interactions
  - PE2_7Nuclear and particle astrophysics
  - PE2_9 Electromagnetism
  - PE2_10Atomic, molecular physics
  - PE2_11Ultra-cold atoms and molecules
  - PE2_18Equilibrium and non-equilibrium statistical mechanics: steady states and dynamics
  - PE2_14Lasers, ultra-short lasers and laser physics
  - PE2_17Metrology and measurement
  - PE2_16Non-linear physics
  - PE2_12Optics, non-linear optics and nano-optics
  - PE2_13Quantum optics and quantum information
  - PE2_15Thermodynamics
- PE1Mathematics
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  - PE1_8Analysis
  - PE1_7Topology
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  - PE1_11Theoretical aspects of partial differential equations
  - PE1_13Probability
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  - PE1_15Generic statistical methodology and modelling
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  - PE1_19Scientific computing and data processing
  - PE1_2Algebra
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  - PE1_21Application of mathematics in sciences
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  - PE1_16Discrete mathematics and combinatorics
  - PE1_17Mathematical aspects of computer science
  - PE1_3Number theory
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  - PE3_1Structure of solids, material growth and characterisation
  - PE3_2Mechanical and acoustical properties of condensed matter, lattice dynamics
  - PE3_3Transport properties of condensed matter
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  - PE11_12Semi-conducting and magnetic materials engineering
  - PE11_13Metamaterials engineering
  - PE11_14Computational methods for materials engineering
LSLife Sciences
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  - LS1_5Lipid biology
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  - LS1_11Chemical biology
  - LS1_12Protein design
  - LS1_13Early translational research and drug design
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  - LS2_4Gene regulation
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  - LS2_7Transcriptomics
  - LS2_8Proteomics
  - LS2_9Metabolomics
  - LS2_10Glycomics/Lipidomics
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  - LS2_12Biostatistics
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  - LS2_16Innovative methods and modelling in integrative biology
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- LS4Physiology in Health, Disease and Ageing
  - LS4_1Organ and tissue physiology and pathophysiology
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  - LS3_2Cell senescence, cell death, autophagy, cell ageing
- LS5Neuroscience and Disorders of the Nervous System
  - LS5_1Neuronal cells
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  - LS5_16Systems and computational neuroscience (e.g. modelling, simulation, brain oscillations, connectomics)
  - LS5_18Innovative methods and tools for neuroscience
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SHSocial Sciences and Humanities
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