6533b856fe1ef96bd12b22a5
RESEARCH PRODUCT
Is local stiffness, as measured by radio frequency, more sensitive than intima-media thickness?
G. NovoR. Di MiceliS. Novosubject
AdultCarotid Artery DiseasesMaleCarotid Artery CommonMiddle AgedPulse Wave AnalysisCardiovascular diseaseSettore MED/11 - Malattie Dell'Apparato CardiovascolareCarotid Intima-Media ThicknessElasticityCarotid intima-media thickneYoung AdultVascular StiffnessROC CurvePredictive Value of TestsRisk FactorsArea Under CurveCase-Control StudiesVascular stiffneElasticity Imaging TechniquesHumansFemaleCardiology and Cardiovascular MedicineVascular stiffnessCarotid intima-media ticknesscardiovascular diseasesdescription
Aim: The aim of our study was to explore the changes in common carotid arterial intima-media thickness (CCA IMT) and local arterial stiffness to evaluate, non-invasively, early vascular disease in patients with cardiovascular (CV) risk factors and "normal" carotid IMT (6.05 m/s better identified, among patients with IMT <0.9mm, those with cardiovascular risk factors (sensitivity 82.0 % specificity 62.0 %; AUC 0.73). Conclusion. Increased stiffness is a result of change both in quantity and quality of the arterial wall. Arterial functional changes and distention alterations may herald the onset of vascular disease before manifestation of symptoms or detection of preclinical atherosclerotic lesions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-11-12 | International angiology : a journal of the International Union of Angiology |