6533b856fe1ef96bd12b238c

RESEARCH PRODUCT

Impact de l'âge dans le cancer du sein : du diagnostic à la qualité de vie des patientes

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Numerous studies have shown that older women with breast cancer are undertreated in comparison with the youngest. Although several reports suggest strong socio-economic and geographic inequalities in the disease stage at diagnosis and in quality of life in breast cancer patients, the effects of these factors according to age are largely unknown in France. The objectives of this work were to determine the impact of socio-economic and geographic disparities on disease stage in breast cancer patients according to age, to describe treatments and relative survival factors in breast cancer patients according to age, and to identify age-related socioeconomic and clinical determinants of quality of life among breast cancer survivors five years after the diagnosisThe results showed that living in a deprived area was linked to advanced-stage breast cancer at diagnosis only in women aged 50-74 years old. The use of breast conserving surgery decreased in older women while the proportions of women without treatment increased with age. Furthermore, survival was poor in elderly women. Finally, the results showed that, five years after breast cancer diagnosis in older women, only comorbidities and a low socio-economic status decreased quality of life scores.To improve survival and quality of life in elderly patients, a multidisciplinary approach by a comprehensive geriatric assessment, is a major step in breast cancer management as it can lead to individualized care for elderly patients with breast cancer.