6533b857fe1ef96bd12b3aaa

RESEARCH PRODUCT

Nucleophilic reactions in the indole series: displacement of bromine under phase transfer catalysis

Girolamo CirrincioneAnna CarbonePaola BarrajaPatrizia Diana

subject

Indole testBromineOrganic Chemistrychemistry.chemical_elementSettore CHIM/08 - Chimica FarmaceuticaBiochemistryCombinatorial chemistryCatalysisNucleophilechemistryPhase (matter)Drug DiscoveryNUCLEOPHILIC REACTIONSNucleophilic substitutionOrganic chemistryAcid hydrolysis

description

A novel synthetic approach for the synthesis of 3-substituted indoles by nucleophilic substitution of 3-bromo derivatives under phase transfer catalysis (PTC) was reported.

yearjournalcountryeditionlanguage
2008-12-01Tetrahedron
https://doi.org/10.1016/j.tet.2008.10.022