6533b857fe1ef96bd12b42f2
RESEARCH PRODUCT
false
subject
medicine.medical_specialtySpeech perceptionRepetition (rhetorical device)Supplementary motor areaGeneral Neurosciencemedia_common.quotation_subject05 social sciencesCTBSContext (language use)Audiology050105 experimental psychologyTask (project management)03 medical and health sciences0302 clinical medicinemedicine.anatomical_structurePerceptionotorhinolaryngologic diseasesmedicine0501 psychology and cognitive sciencesPsychology030217 neurology & neurosurgerySentencemedia_commondescription
The pre-supplementary motor area (pre-SMA) is engaged in speech comprehension under difficult circumstances such as poor acoustic signal quality or time-critical conditions. Previous studies found that left pre-SMA is activated when subjects listen to accelerated speech. Here, the functional role of pre-SMA was tested for accelerated speech comprehension by inducing a transient "virtual lesion" using continuous theta-burst stimulation (cTBS). Participants were tested (1) prior to (pre-baseline), (2) 10 min after (test condition for the cTBS effect), and (3) 60 min after stimulation (post-baseline) using a sentence repetition task (formant-synthesized at rates of 8, 10, 12, 14, and 16 syllables/s). Speech comprehension was quantified by the percentage of correctly reproduced speech material. For high speech rates, subjects showed decreased performance after cTBS of pre-SMA. Regarding the error pattern, the number of incorrect words without any semantic or phonological similarity to the target context increased, while related words decreased. Thus, the transient impairment of pre-SMA seems to affect its inhibitory function that normally eliminates erroneous speech material prior to speaking or, in case of perception, prior to encoding into a semantically/pragmatically meaningful message.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-05-29 | Frontiers in Neuroscience |