6533b857fe1ef96bd12b43da

RESEARCH PRODUCT

Influence of Macrophage Activation on the Synthesis of Complement Components C2, C3, C4

Dieter Bitter-suermannBernd ZankerHans-peter Hartung

subject

Guinea pigChemistryMacrophageBiological activitySecretionComplement (complexity)Cell biologyComplement components

description

Macrophages are a major site of complement synthesis. In the guinea pig production of complement components C1, C2, C4, C3, D, B, and P by peritoneal macrophages has been demonstrated (reviewed in Ref. 1). Whereas marked differences exist in biological activity between resident, elicited and activated macrophages (2), we investigated whether this holds true for the synthesis and secretion of complement components C2, C3, and C4.

yearjournalcountryeditionlanguage
1982-01-01
https://doi.org/10.1007/978-1-4684-4394-3_55