6533b857fe1ef96bd12b5056
RESEARCH PRODUCT
Template-controlled synthesis of chiral cyclohexylhemicucurbit[8]uril
Toomas TammIvar JärvingKari RissanenMaria FomitšenkoRiina AavSandra KaabelFilip TopićMario ÖErenIndrek ReileElena Prigorchenkosubject
Metals and AlloysFormaldehydeGeneral Chemistryhost-guest sytemscycHC synthesisCombinatorial chemistryCatalysisSurfaces Coatings and FilmsElectronic Optical and Magnetic Materialschemistry.chemical_compoundchemistryCovalent bondYield (chemistry)Materials ChemistryCeramics and Compositesta116description
Enantiomerically pure cyclohexylhemicucurbit[8]uril (cycHC[8]), possessing a barrel-shaped cavity, has been prepared in high yield on a gram scale from either (R,R,N,N')-cyclohex-1,2-diylurea and formaldehyde or cycHC[6]. In either case, a dynamic covalent library is first generated from which the desired cycHC can be amplified using a suitable anion template.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-06-11 | Chemical Communications |