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RESEARCH PRODUCT

A Study of Lipid-Lipid and Lipid-Polypeptide Interactions by High Performance Liquid Chromatography

Lorenzo BracoF. M. GoñiConcepción AbadJuan E. Figueruelo

subject

ChromatographyChemistrytechnology industry and agricultureIonophoreSolvationPhospholipidHigh-performance liquid chromatographyHydrophobic effectchemistry.chemical_compoundMembranePhosphatidylcholinepolycyclic compoundsMolecular Medicinelipids (amino acids peptides and proteins)Tetrahydrofuran

description

Abstract Ternary systems containing phosphatidylcholine-cholesterol, phosphatidylcholine-gramicidin A or cholesterol-gramicidin A in tetrahydrofuran have been examined by high performance liquid chromatography. Preferential solvation of cholesterol and especially gramicidin A by phosphatidylcholine is observed. These results are interpreted in terms of hydrophobic interactions between membrane components.

https://doi.org/10.1080/01483918408074067