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RESEARCH PRODUCT
Xanthogranulomatous Cholecystitis
G. GenovaAragona FAda Maria FlorenaVito FrancoMario StellaG. Campesisubject
Pathologymedicine.medical_specialtymedicine.anatomical_structurebusiness.industryGallbladdermedicineCell BiologyFoamy histiocytesbusinessInflammatory lesionXanthogranulomatous CholecystitisPathology and Forensic Medicinedescription
Summary Xanthogranulomatous cholecystitis (XC) is a chronic inflammatory lesion of the gallbladder histologically characterized by the presence of varying amounts of foamy histiocytes in the inflammatory infiltrate. In this study a review of 63 cases selected from 1207 surgically removed gallbladders is presented; the percentage found (5.2%) is slightly higher than that of previous reports showing that XC is less uncommon than generally believed. A detailed microscopic study is performed: the authors observed according to the histological features particularly the different patterns of distribution of the inflammatory infiltrate and postulate the existence of three subtypes of XC: multinodular, focal and diffuse XC. Finally, the main etiopathogenetic hypotheses are briefly discussed.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1990-06-01 | Pathology - Research and Practice |