6533b858fe1ef96bd12b6c90

RESEARCH PRODUCT

ChemInform Abstract: Pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine: A New Ring System Through Dimroth Rearrangement.

Noemi GambinoChiara PatellaAntonino LauriaIlenia AbbateArturo SilvestriGiampaolo BaroneAnna Maria Almerico

subject

chemistry.chemical_compoundPyrimidineChemistryStereochemistryIntercalation (chemistry)General MedicineRing (chemistry)Dimroth rearrangementD-1

description

Abstract Derivatives of the new ring system pyrazolo[3,4- d ][1,2,3]triazolo[1,5- a ]pyrimidine were synthesized from the corresponding angular isomers, through a Dimroth rearrangement, in quantitative yields. Preliminary computational studies demonstrated that this class of compounds could be a good candidate as DNA intercalating agents.

yearjournalcountryeditionlanguage
2008-12-09ChemInform
https://doi.org/10.1002/chin.200850154