6533b858fe1ef96bd12b6ca3

RESEARCH PRODUCT

- conformational preference of , -9-oxobicyclo[3.3.1]nonane-2,4-dicarboxylic acid

C. IglesiasPelayo Camps

subject

chemistry.chemical_classificationchemistry.chemical_compoundDicarboxylic acidchemistryBicyclic moleculeStereochemistryOrganic ChemistryDrug DiscoveryNuclear magnetic resonance spectroscopyCarbon-13 NMRNonaneBiochemistry

description

Abstract The 1 H and 13 C nmr spectra of exo , exo -9-oxobicyclo[3.3.1]nonane-2,4-dicarboxylic acid, 3, in DMSO-d 6 or alkaline D 2 O, clearly show that it exists in a boat - chair -conformation with equatorial carboxyl groups, thus being the first case of boat - chair preference of a bicyclo[3.3.1] nonan-9-one due to the presence of exo , exo -2,4- substituents.

yearjournalcountryeditionlanguage
1985-01-01Tetrahedron Letters
https://doi.org/10.1016/s0040-4039(00)98237-6