Enzymatische hydrolyse hydrophiler ester durch lipasen - eine milde carboxydeblockierung von peptiden und glycopeptiden

6533b859fe1ef96bd12b75e3

RESEARCH PRODUCT

Enzymatische hydrolyse hydrophiler ester durch lipasen - eine milde carboxydeblockierung von peptiden und glycopeptiden

Horst Kunz Danuta Kowalczyk Peter Braun Günther Braum

subject

chemistry.chemical_classification Aqueous solution Stereochemistry Organic Chemistry Triacylglycerol lipase Peptide Biochemistry Glycopeptide Hydrolysis chemistry.chemical_compound Enzyme chemistry Drug Discovery Acetone Organic chemistry Selectivity

description

Abstract The markedly hydrophilic 2-(N-morpholino)ethyl (MoEt) esters of protected peptides and glycopeptides are selectively and efficiently cleaved by lipases in water/acetone (10:1) at pH 7.

year	journal	country	edition	language
1993-05-01	Tetrahedron Letters

https://doi.org/10.1016/s0040-4039(00)93392-6

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