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RESEARCH PRODUCT
Poly(ethylene glycol) diacrylate-based solid-phase extraction for determination of sulfonamides in meat samples
Ernesto F. Simó-alfonsoJosé Manuel Herrero-martínezMaría Vergara-barberánMaría Jesús Lerma-garcíaAncuta Mogasubject
SorbentChromatographyChemistryElution010401 analytical chemistryExtraction (chemistry)02 engineering and technologySulfapyridine021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesAnalytical Chemistrychemistry.chemical_compoundmedicineSulfamonomethoxineSolid phase extraction0210 nano-technologySulfaguanidineEthylene glycolSpectroscopymedicine.drugdescription
Abstract In this work, a sorbent based on poly(ethylene glycol) diacrylate (PEGDA) polymer has been synthesized for solid-phase extraction (SPE) of sulfonamides (sulfaguanidine, sulfadiazine, sulfathiazole, sulfapyridine, sulfamethazine, sulfamonomethoxine, sulfamethoxazole, sulfisoxazole) from different meat matrices, which were subsequently determined by HPLC-DAD. Several extraction parameters such as loading and elution solvents as well as other variables (loading capacity, breakthrough volume and reusability) influencing on the analytical performance of the sorbent were optimized. Under the optimal conditions, the developed method was successfully applied to determine the eight sulfonamides in meat samples including pork bacon, pork liver and chicken muscle. Satisfactory recovery values of sulfonamides comprised between 70% and 108% were obtained. The results demonstrated the suitability of the PEGDA-700 material to be used as sorbent in SPE for effective clean-up and extraction of sulfonamides in complex samples.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-09-01 | Microchemical Journal |