6533b859fe1ef96bd12b77e3
RESEARCH PRODUCT
Systematic study of SYBR green chromophore reveals major improvement with one heteroatom difference
Ville SaarnioJohanna M. AlarantaTanja Lahtinensubject
BrightnessMolecular StructureHeteroatomBiomedical EngineeringDNAGeneral ChemistryGeneral MedicineDiaminesChromophorePhotochemistrychemistry.chemical_compoundchemistryQuinolinesSYBR Green INucleic acidRNAGeneral Materials ScienceBenzothiazolessense organsCyanineFluorescent Dyesdescription
Five nucleic acid binding cyanine dyes were synthesized and their photophysical properties were evaluated. Changing a single heteroatom in the chromophore causes major differences both in brightness and photostability between the dyes. With such alteration, the brightness of the chromophore increased two-fold compared to the one found in SYBR Green I.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-04-28 | Journal of Materials Chemistry B |