6533b859fe1ef96bd12b78f2
RESEARCH PRODUCT
(5R)-5-[(1R)-2,2-Dichloro-1-methylcyclopropyl]-2-methylcyclohex-2-en-1-one
Corrado RizzoliLarbi El FirdoussiMohamed Anoir HarradMustapha Ait AliBrahim Boualysubject
CrystallographyChemistryPotassiumchemistry.chemical_elementGeneral ChemistryCondensed Matter PhysicsRing (chemistry)BioinformaticsMedicinal chemistryChlorideOrganic PapersCatalysisCrystalsymbols.namesakeQD901-999medicinesymbolsGeneral Materials Sciencevan der Waals forcemedicine.drugdescription
The title compound, C(11)H(14)Cl(2)O, was synthesized by the reaction of a dichloro-methane solution of (R)-carvone and potassium tert-butano-late in the presence of a catalytic amount of benzyl-triethyl-ammonium chloride in chloro-form. The cyclo-hexene ring adopts a half-boat conformation. The cyclo-propyl ring is unsymmetrical, the shortest C-C bond being distal to the alkyl-substituted C atom. The crystal packing is stabilized only by van der Waals inter-actions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-06-01 | Acta Crystallographica Section E: Structure Reports Online |