6533b859fe1ef96bd12b7f95

RESEARCH PRODUCT

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subject

chemistry.chemical_classificationAqueous solution010405 organic chemistryPeptideGeneral ChemistryChromophore010402 general chemistry01 natural sciencesCombinatorial chemistryFluorescence0104 chemical sciencesSupramolecular polymerschemistryAmphiphileSelf-assemblyLuminescence

description

The pH-responsive nature of two self-assembled NDI-peptide amphiphile conjugates is reported. The diethoxy substituted NDI showed a pH-dependent assembly behaviour, as expected. In contrast, the isopropylamino- and ethoxy-substituted NDI based supramolecular polymer was stable at acidic and basic aqueous conditions. This finding highlights how subtle changes in the molecular design of π-stacked chromophore-peptide conjugates have a drastic impact on their equilibrium structure and ultimately functional properties.