6533b859fe1ef96bd12b8263
RESEARCH PRODUCT
Asymmetric Organocatalytic Wittig [2,3]-Rearrangement of Oxindoles
Tõnis KangerMariliis KimmSandra KaabelSandra KaabelKari RissanenIvar JärvingMaksim Ošekasubject
asymmetric organocatalytic wittigIndolesStereoisomerism010402 general chemistry01 natural sciencesBiochemistryCatalysisCatalysischemistry.chemical_compoundCombinatorial Chemistry TechniquesOrganic chemistryOxindolePhysical and Theoretical Chemistryta116Molecular Structure010405 organic chemistryOrganic ChemistrySquaramideEnantioselective synthesisStereoisomerismAmidesOxindoles0104 chemical scienceschemistryWittig reactionEnantiomerdescription
A highly enantioselective organocatalytic [2,3]-rearrangement of oxindole derivatives is presented. The reaction was catalyzed by squaramide, and this provides access to 3-hydroxy 3-substituted oxindoles in high enantiomeric purities.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-03-04 | Organic Letters |