6533b85afe1ef96bd12b8ad5

RESEARCH PRODUCT

Characterization and synthesis of O- and N-tosylated N,N-bis(2-aminophenyl)isophthalamide based ligands

Kirsi SalorinneMaija NissinenKatri Toikkanen

subject

Inorganic Chemistrychemistry.chemical_classificationCrystallographyBase (chemistry)ChemistryOrganic ChemistryX-ray crystallographyNuclear magnetic resonance spectroscopySelectivityMass spectrometryMedicinal chemistrySpectroscopyAnalytical Chemistry

description

Abstract A synthetic strategy for the preparation of O - and N- tosylated N , N -bis(2-aminophenyl)isophthalamide based ligands is described. It was observed that selectivity in O - and N -tosylation could be achieved by performing the reaction at low temperatures in the presence of an appropriate base. The obtained O - and N -tosylated products were characterized by means of NMR and mass spectroscopy, and X-ray crystallography.

yearjournalcountryeditionlanguage
2009-12-01Journal of Molecular Structure
https://doi.org/10.1016/j.molstruc.2009.09.015