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RESEARCH PRODUCT
Topical glaucoma medications – Clinical implications for the ocular surface
Fredrik FineideNeil S. LagaliMuhammed Yasin AdilReiko AritaMiriam KolkoJelle VehofTor P. Utheimsubject
Oorganisk kemiPreservatives PharmaceuticalGlaucomaMeibomian gland dysfunctionInorganic ChemistryOphthalmologyVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Oftalmologi: 754:Medisinske Fag: 700 [VDP]TearsTopical medicationsHumansEyedropsDry Eye SyndromesDry eye diseaseOphthalmic SolutionsDry eye disease; Eyedrops; Glaucoma; Meibomian gland dysfunction; Topical medicationsAntihypertensive AgentsIntraocular Pressuredescription
Glaucoma is a leading cause of irreversible blindness. The use of topical eye drops to reduce intraocular pressure remains the mainstay treatment. These eye drops frequently contain preservatives designed to ensure sterility of the compound. A growing number of clinical and experimental studies report the detrimental effects of not only these preservatives but also the active pharmaceutical compounds on the ocular surface, with resultant tear film instability and dry eye disease. Herein, we critically appraise the published literature exploring the effects of preservatives and pharmaceutical compounds on the ocular surface. publishedVersion
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2022-10-01 |