6533b85afe1ef96bd12b941f

RESEARCH PRODUCT

ChemInform Abstract: New Conditions for the Generation of Dianions of Carboxylic Acids.

Salvador GilMargarita ParraIsabel CasadesEva M. BrunRamon Mestres

subject

chemistry.chemical_classificationDiethylaminechemistry.chemical_compoundPiperazinechemistryCarboxylic acidButyllithiumchemistry.chemical_elementLithiumGeneral MedicineMedicinal chemistryCatalysisOctane

description

Abstract Lithium carboxylic acid enediolates are generated efficiently using lithium amides prepared from thienyllithium or butyllithium and either diethylamine, piperazine, N,N′-dibenzylethylenediamine, N-benzylpiperazine or 1,3,3-trimethyl-6-azabicyclo[3.2.1]octane, even in catalytic amounts.

https://doi.org/10.1002/chin.199842096