6533b85afe1ef96bd12b95b6

RESEARCH PRODUCT

Evaluation of the Disk Diffusion Method Compared to the Microdilution Method in Susceptibility Testing of Anidulafungin against Filamentous Fungi

Carmelo Massimo MaidaElisabetta SpreghiniEmanuele AmodioLaura TrovatoMaria Eleonora MiliciSalvatore Massimo OliveriFrancesco BarchiesiGiorgio Scalise

subject

Microbiology (medical)Susceptibility testingAntifungal AgentsDisk Diffusion; Yeasts; CaspofunginDisk diffusion anidulafungin MIC MECMycologyMicrobial Sensitivity TestsBiologyAnidulafunginSettore MED/42 - Igiene Generale E ApplicataDisk DiffusionMicrobiologyEchinocandinsCaspofunginYeastsmedicineHumansAgar diffusion testFood scienceAspergillus Anidulafungin Disk Diffusion1 3 β glucan synthaseAnidulafungineBroth microdilutionFungiAnidulafunginaMycosesAnidulafunginmedicine.drug

description

ABSTRACT Susceptibility testing of anidulafungin (AFG) against 32 mold isolates showed an excellent correlation between disk diffusion (DD) and broth microdilution methods. Based on our data, a 2-μg disk of AFG and a 24-h reading time might represent the best parameters for AFG DD testing against filamentous fungi.

yearjournalcountryeditionlanguage
2008-12-01Journal of Clinical Microbiology
https://doi.org/10.1128/jcm.01088-08