6533b85bfe1ef96bd12ba20b

RESEARCH PRODUCT

Network intervention analysis to assess the trajectory of change and treatment effects associated with the use of online guided self-help for anorexia nervosa

Francesca PellegrinoJanet TreasureValentina CardiGaia AlbanoGiammarco CascinoSuman AmbwaniAlessio Maria Monteleone

subject

Adultanorexia nervosa network intervention analysis outcome random ized clinical trial treatment effectsAnorexia Nervosaanorexia nervosa; network intervention analysis; outcome; randomized clinical trial; treatment effectsAnxietylaw.inventionSelf-helpRandomized controlled triallawIntervention (counseling)Settore M-PSI/08 - Psicologia ClinicaMedicineHumansBiological PsychiatryDepression (differential diagnoses)network intervention analysiMotivationbusiness.industrynetwork intervention analysistreatment effectsrandomized clinical trialAnxiety DisordersPsychiatry and Mental healthMoodAnorexia nervosa (differential diagnoses)outcomeAnxietyPshychiatric Mental Healthmedicine.symptomAugmentbusinessSocial AdjustmentClinical psychology

description

Aim The aim of this study was to use the innovative technique of Network Intervention Analysis (NIA) to examine the trajectory of symptom change associated with the use of a digital guided self-help intervention (RecoveryMANTRA) to augment treatment as usual in adult anorexia nervosa. Methods Self-reported eating disorder symptoms and mood (stress, anxiety and depression), work and social adjustment, motivation and treatment (Treatment as usual + RecoveryMANTRAand Treatment as usual) were included as nodes in the network and examined using NIA. Networks were computed at baseline (n = 88, 99), at end of treatment (6 weeks, n = 71, 75) and at 6- (n = 58, 63) and 12-month (n = 52, 63) follow-up. Results RecoveryMANTRA was associated with a direct effect on anxiety, shape concern and restraint at the end of the intervention. This effect was not maintained at follow-up. There were no direct effects of RecoveryMANTRA on motivation, stress and depression. Conclusions These findings indicate that RecoveryMANTRA exerts a direct effect on eating disorder symptoms and anxiety. NIA is a promising method to evaluate trajectories of clinical change and direct and indirect effects of a therapeutic intervention compared to a control condition.

10.1111/eip.13064http://hdl.handle.net/10447/466279