6533b85bfe1ef96bd12ba8e4

RESEARCH PRODUCT

6-Amino-7-Azaindoles synthesis from 2,6-diamino pyridine and diols

Ana C. CuñatAmelia Bou-puertoCarlota Martinez-morroRafael Ballesteros-garridoNerea Gonzalez-sanchisRafael BallesterosDelia Bellezza

subject

chemistry.chemical_compoundChemistryYield (chemistry)Organic ChemistryDrug DiscoveryCondensationPyridineOrganic chemistryBiochemistryPyrroleCatalysis

description

Abstract 6-Amino-7-azaindole has been prepared by combination of diaminopyridine and diols by means of an acceptorless dehydrogenative condensation. In addition, amino pyridines may also yield towards pyrrolo[3,2-b]pyrrole systems. All of these transformation have been performed with accessible heterogeneous catalysts: Pd/C and ZnO.

https://doi.org/10.1016/j.tetlet.2021.153460